Sentence examples for changes in the modification from inspiring English sources
Furthermore, the dispersion of CNCs in PLA matrices is profoundly influenced by relatively small changes in the modification chemistry, in this case, appending lactate vs. acetate groups.
Changes in the modification yield are reflected in the mechanical properties and DMA data of photo-responsive elastomers are illustrated in dependence on the number of attached anthracene groups.
Furthermore, transcription itself leads to changes in the modification pattern of the underlying chromatin [29].
Changes in the underlying DNA are rarely associated with changes in the modification carried by any overlying nucleosome.
The second file contains biochemical data relating to the changes in the modification state (typically phosphorylation) of proteins following stimulation under various conditions.
Variable-temperature experiments demonstrate both crystallization effects and changes in the modifications.
VPA treatment caused no changes in the modifications tested at DR5, but DR2 showed an approximately 2-fold increase in H3K9ac and H3K27ac, along with a small diminution of H3K27me3.
These reversible transitions are based on complex epigenetic regulatory mechanisms (e.g. the induction of changes in the modifications of chromatin-associated histones) during epithelial-mesenchymal transitions [ 385, 386].
Therefore, we sought to discover patterns of histone modifications that contribute to epigenomic reprogramming during EMT, and how changes in these modifications relate to the signaling events that are known to establish the mesenchymal phenotype.
The exit from the self-renewing state is accompanied by changes in the covalent modifications of histones, for example, an increase in the silencing-associated histone H3K9me2 and H3K9me3 marks on the chromatin and removal of H3K27me3.
The phenotype of the G9a/Glp1 knockout is embryonically lethal [ 24]; however, it is unclear whether this is due to changes in the histone modifications or in other G9a/Glp1 targets [ 32].
