Sentence examples for changes in the isotype profile from inspiring English sources

Maturation of an immune response is also reflected by changes in the isotype profile of the antibody response.

The insulin dose administered induced a modest change in the IA isotype profile.

An alternative explanation may be that the elevated levels of reactivity seen in HIV-positive serum are specific for the IgG isotypes and that the elevated levels of the isotype profile of Msg-specific antibodies may be skewed in healthy persons and HIV-positive patients.

The isotype profile appears to be different depending on the subset studied and the ligand used.

Finally, we examined if the route of immunization influenced the isotype profile.

In IM immunization, the serum IgG responses were dose related and the Th1 responses were predominant as shown by the isotype profile before and post-challenge and the cytokine data.

FL- or GM-CSF-treated mice injected with soluble ovalbumin display dramatic increases in antigen-specific antibody titers, but the isotype profiles seem critically dependent on the cytokine used.

The isotype profiles (IgG1 and IgG2a) of serum antibody responses were also assessed by ELISA for the same time-points for the viral-vector immunized mice (B) and the protein-in-adjuvant immunized mice (C) (n.d., not detected).

For each B cell sample, we quantified the frequency of IgH sequences expressing a given isotype and examined the relationship between the isotype profiles to the mutation status.

Due to the endogenous expression of tubulin isotypes it is possible that the change in the isotype composition in the mt lattice as a consequence of exogenous expression of TUBB3 or TUBB is not as dramatic as the depletion of individual tubulin isotypes.

Using IgG1 and IgG2a as markers for Th2- and Th1-type response respectively, we also assessed the IgG isotype profile of the antibodies generated after vaccination with Pfs25 and Pfs25-IMX313 construsingusing both viral-vector and protein-in-adjuvant regimes.