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Variability in cell cycle (both in cell lines and primary cells), expression levels and availability of different virus receptors, the variable activation state of individual cells, changes in fluid flow and diffusion can all contribute to changes in spreading characteristics [37] [41].
Thus, the increased apical area of C85S cells is associated with morphological changes in spreading and flattening.
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The dramatic change in spreading orientation and rate after 20 Ma is interpreted by Sdrolias et al. (2004) as the expression of PSP rotation.
We observed no change in spreading capacity in MEFs with native CK-B, but MEFs with MYR-anchored CK-B covered a 25% larger area than MEFs without CK-B or with native CK-B under the experimental conditions used, confirming the importance for local CK-B in actin-dependent cell processes.
These results imply frequent dysregulation of H3K27me3 spreading and less prevalent changes in H3K9me3 spreading.
The area between approximately 14.5° and 15.5° N near 130° E is such an example; however, this may have been caused by the reorganization associated with slight changes in the spreading direction rather than a slower spreading rate (Deschamps et al.2002,2008).2002,2008
Biochemical mechanotransduction implies the conversion of mechanical forces (e.g. changes in cell spreading and morphology from changing surface topography) into biochemical signal via biomolecules.
The first set of charts shows the changes in spreads since July 22, while the second set of charts shows the long-term trend beginning in 1994.
While the symmetric adjustment dynamics for different maturities are slightly different, they all imply changes in spreads between 0.0 and 0.2 percentage points when the adjustment is completed.
Changes in the spreading coefficient and solvent polarity led to the formation of different morphologies.
Similarly, integrin expression and the geometrical maturation of adhesions they regulate have been correlated with important changes in cell spreading and phenotype.
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