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Degenerative changes in skin tissue are readily visible, so they can be detected easily [ 27].
Our findings demonstrated that the GMF-TG mice had short lifespans and showed premature degenerative changes in skin tissue (e.g., reduced hair regrowth).
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Cryopreservation of tissue-engineered human dermal replacement plays an important role in skin tissue engineering and skin banking.
The endogenous ABA content in skin tissue of cv.
E-selectin immunolocalisation was performed in skin tissue sections.
Indeed, immunofluorescence staining for BrdU-incorporated cells in skin tissues revealed marked changes of cellular proliferation patterns in the basal layers and hair follicles of RASSF9−/− mice versus WT. (Figure 4A and B).
(K) Quantification of α-SMA+ fibroblasts in skin tissues (n = 10 per group).
(I) mRNA expression of IL-17A, IL-17F, and IL-22 in skin tissues.
(4– 6) For example, we showed that increased ANGPTL2 expression in skin tissues promotes inflammation and accelerates carcinogenesis in a chemically-induced skin squamous cell carcinoma mouse model by increasing susceptibility to "preneoplastic change" and "malignant conversion".
[5] Chronic repeated sunlight exposure can also induce degenerative changes in skin cells, fibrous tissue, and blood vessels, leading to visible signs of actinic skin damage, [4] which is partially characterized by telangiectasia, solar elastosis, and actinic keratoses.
In another experiment, CNTs were subcutaneously implanted into BALB/c mice and CD4+ and CD8+ T-cells in peripheral blood, and the histopathological changes on skin tissues were measured [13].
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