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There were no reproducible changes in sections of skin, muscle, fat, intestine, liver, kidney, spleen, or heart.
Pathological changes in sections of femoral bone marrows showed that irradiation reduced marrow cellularity, thereby resulting in the absence of erythroid, rare myeloid and megakaryocytic cells.
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Importantly, the mean weight of animals treated with L.s.-P or its fractions did not differ from that of control animals, and no significant histopathologic changes were observed in sections of liver, spleen and lung of treated versus untreated mice (data not shown), suggesting that fucoidans or their purified fractions have no substantial toxic effects at least at the concentrations tested.
No tissue changes were noted in sections of kidneys, testes, or skeletal muscles from Asah1P361R/P361R mice.
Histologically pathological changes are seen in sections of pancreas, liver and kidney.
Rempel et al (2000) observed a tumour grade-dependent surge of CXCR4 mRNA levels in glioblastoma multiforme and that this receptor is mainly expressed in regions of angiogenesis and degenerative, necrotic, and microcystic changes rather than in sections of rapid cell proliferation.
The epidermal changes were most prominent in sections of the affected dorsal trunk, ear and tail skin (Figure 3A C).
To investigate the pathological changes in primates, sections of baboon trachea, right and left lower lobe bronchi, and distal bronchi and bronchioles were obtained (Figure 9).
Pathological changes in the sections of the intestinal segments were assessed using a modified scoring procedure (Satoh et al., 1997).
We performed a morphological analysis of the changes observed and quantified the microglia in sections of cerebral cortex and spinal cord [24].
Note that we use images from INRIA database to perform the experiments under different scale changes in Section 7.4, because the test set of images with scale changes in Oxford database is a subset of that in INRIA database.
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