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In the absence of pathological deviations from healthy reference range for a given outcome at baseline, therapeutic-induced changes in said outcomes are difficult to interpret.
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Astronomers would measure very small changes in, say, Earth's orbit, that were caused by the attraction of Venus.
But the smaller company was at the mercy of the larger one, and of changes in, say, the algorithm that powers News Feed.
The first and main reason is that the 'population momentum' embedded in age-sex pyramids in base year 2015 leaves little room for effects of changes in, say, fertility and mortality, due to a political reorientation between 2015 and 2035.
Note that in treating a state as, for all intents and purposes, a distinct labor market, we are assuming that changes in, say, labor supply within a given state are not driven by inter-state migration.
Vehicle thefts are usually reported to the police and so we are more confident that the trend identified in Japan and Taiwan is not simply a product of changes in, say, police activity and/or recording practices.
Does a change in, say, serum potassium levels predict that a patient with multiple sclerosis will soon suffer a flare-up?
"There have been lots of changes in Cambodia," said Buthom.
"It gives you a new direct probe to look at conformational changes in proteins," says Sheves.
"Nothing's changed in two years," said Robert Goodman.
"Clearly there is a change in environment," said Maj.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com