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Adjusted odds ratios were estimated by mixed- effects logistic regression models to describe how 90-day post-discharge mortality differed with changes in protein delivery.
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These copolymers may be useful in protein delivery systems.
Major research issues in protein delivery include the stabilization of proteins in delivery devices and the design of appropriate protein carriers in order to overcome mucosal barriers.
CYP2J3 gene delivery reversed changes in protein expression and phosphorylation induced by fructose in rats.
This method showed a remarkable sensitivity to changes in protein structures, including protein denaturation and even small protein damage.
FRET techniques are sensitive to changes in intra- and inter- molecular distances and can thus report relatively small changes in protein structures and protein-protein interactions.
Here, more substantial sequence changes are observed which trigger some changes in protein disorder (dynamics) profiles.
Transmission electron microscopy showed significant changes in protein morphology as polymer protein complexation progressed with major increase in the diameter of the protein aggregate (180%).
Color bar indicates changes in protein abundance.
c) Changes in protein concentrations.
BSA was used as a model protein to study the adsorption and sustained release of proteins from the CFCA-Ap particles in simulated protein delivery experiments.
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