Sentence examples for changes in promoters from inspiring English sources

Next, we reasoned that specific selective pressure demands could be met by fixing changes in promoters and coding regions alike.

The adult offspring of high compared to low maternal care mothers show epigenetic changes in promoters, exons, and gene ends associated with higher transcriptional activity across many genes within the locus examined.

Next, we performed a functional analysis with the aim of answering two main questions: (i) Is there a functional specialization of promoters and proteins so that genes related to some biological processes evolve mainly through changes in promoters while genes related to other biological processes evolve through changes in protein-coding regions?

In total, this database contains 1069 mutations (non-synonymous amino-acid changes or nucleotide changes in promoters).

Reduced EWS-FLI1 expression led to widespread epigenetic changes in promoters, enhancers, and super-enhancers, and we identified histone H3K27 acetylation as the most strongly affected mark.

Epigenetic changes in promoters of non-coding RNA genes could result in changes of their expression levels, which subsequently could result in expression changes of downstream protein coding genes in endometrial cancer [ 46] and in changes of the epigenetic landscape [ 47].

A series of replicating promoter-probe vectors utilizing gfp were constructed to examine changes in promoter activity in response to a set of defined conditions (Table 1).

Changes in promoter methylation of osteocalcin gene have been suggested to play a role in osteoblast differentiation and carcinogenesis in human and rat [30] [32].

This suggests that parameter values such as maturation and degradation rates for Gemini are reasonably insensitive to changes in promoter activity.

If these parameters were sensitive to changes in promoter activity, a more significant divergence between RPU measurements obtained via GFP and Gemini would be expected.

Since a single CMV promoter is used to drive fLuc and RLuc expression, the differential response of fLuc and RLuc8 activity to apoptosis also cannot be attributed to any difference or changes in promoter activity.