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Changes in aerated and nonaerated lung volumes after the recruitment maneuver were adequately represented by changes in plateau pressure, respiratory system compliance and recruitable volume.
Poorly aerated lung regions were the main determinant for the observed changes in plateau pressure, respiratory system compliance and recruitable volume.
However, changes in aerated and nonaerated lung after the recruitment manoeuvre were adequately represented by changes in plateau pressure, respiratory system compliance and recruitable volume.
The nitrosative species decrease observed in the present study could therefore be related to some improvement in mechanical stress in these patients, even though no significant changes in plateau pressure or intrinsic positive end-expiratory pressure were observed, probably because their values before salbutamol inhalation were normal.
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With the observed change in plateau pressure for a given Vt, an increase in compliance and an improvement in residual capacity are likely.
Individual values are reported for ARDS (solid circle) and control group (open circle), and black solid lines represent mean values of each group Fig. 3 Relationship between the changes in transpulmonary plateau pressure and airway plateau pressure in control (left panel) and ARDS patients (right panel).
Unfortunately, as can be appreciated from Fig. 1, for a given level of hyperemic flow, CFR strongly depends on changes in the plateau level of resting perfusion.
Alveolar recruitment correlated only with changes in the plateau pressure (r = 0.89), respiratory system compliance (r = 0.82) and parameters obtained from the pressure-volume curve.
All previous changes in the potential plateau, number of plateaus and shape of charging discharging curves can be due to structural re-arrangement in the electrode materials as confirmed by CV curves in Fig. 3c and d.
It does not mean that a change-point in a plateau is never optimal but only that it is not necessary to have change-points in plateaux to achieve optimality.
When searching for the best segmentation of the data, it is therefore unnecessary to look for change-points in plateaux.
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