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We aimed to explore changes in incidence, to estimate changes in survival, and to describe predictors of mortality in UVH patients.
Prevalence changes among young women are often used as a proxy for changes in incidence.
Our analysis seeks to minimise confounding referable to factors other than changes in incidence and case detection rate.
Changes in incidence over time were very similar for younger and older children in the cohort (figure 2B).
This illustrates the difficulty in determining exactly when changes in incidence have occurred given natural random (stochastic) variation, even in large Trusts.
Our method removes the possible negative changes in incidence due to sampling variability when the number of sera tested and change of seroprevalence between two months are small.
For Scenario B, the relationship between actual changes in incidence and changes in the BED-estimates of incidence shows only a weak positive correlation.
ART, by itself, is not likely to lead to substantial changes in incidence unless treatment can be initiated before individuals reach advanced disease [34], [54], [55].
First, a decrease in malarial incidence is expected with increasing age, although in this area of relatively low malaria transmission, changes in incidence with age were modest [19].
Changes in incidence over time were plotted.
We observed no substantial changes in incidence rates over time.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com