Changes in filling rates may result in different curing times for CPB material and thus affect CPB strength.
Our study partially agrees with data obtained by others suggesting that changes in filling pressures are less helpful in this respect than changes in GEDVI [ 21- 26, 26].
It remains possible that differences in capillary hydrostatic pressure existed despite not being reflected in changes in filling volumes or SV.
The fluid loading protocol guided by changes in filling pressures was used to prevent deleterious fluid overloading rather than to guide treatment on the basis of fluid responsiveness, as recently advocated to ensure safety [ 23, 26, 27].
MAP targets were achieved in all patients at all time points (64 ± 3, 84 ± 4; 65 ± 5 mmHg in the LHL group and 84 ± 3; 66 ± 2; 85 ± 5 mmHg in the HLH group at the first, second and third time points), with corresponding changes in filling pressures.
The change in fill factors (FFs) in Figure 3d relates to the influence of the Schottky barrier, Zn0.8Mg0.2O conductivity and device fabrication on recombination.
Since the surface area to volume ratio is very high in microchannels, the surface wettability has a significant effect on microfluidic flow, and as a result a small change of contact angle leads to a larger change in capillary forces, thus making a significant change in filling time (Figure 9).
25 LA enlargement is due to the change in filling dynamics associated with abnormal LV relaxation.
Nonetheless, we acknowledge that the breath-hold maneuver can potentially influence left ventricular filling capacity, and if accompanied by the Valsalva maneuver, a change in filling pressure may happen and possibly alter EDV.
Both the patellar and condylar defects showed a change in filling with time (p = 0.02 and p = 0.02, respectively), the change being apparent at the interval from 24 to 36 weeks (p = 0.003 for patellar defects and p < 0.001 for condylar defects).
