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It made news, but in a way that proved adaptable to the changes in exploration and adventure brought about by advances in science, aviation and technology.
Enrichment has numerous behavioral effects (for reviews see [6], [14], [15]), but has been shown to reduce fear responses [1], [13], [16], increase movement and activity [17] [19], and induce changes in exploration behavior [8], [10], [11], [20], [21].
Indeed, changes in exploration levels have been linked to hippocampal lesion deficits for spontaneous object recognition (Ainge et al., 2006).
This apparatus makes it possible to quantify changes in exploration levels across multiple trials within a single session, during which interference effects should accrue.
Post-hoc analysis of the changes in exploration disclosed a significant NOD × LPS interaction on day 1 and 3 post-treatment, while there was only a trend for interaction on day 2 (p = 0.1).
This potential overlap of processes may prove particularly problematic for interpreting spontaneous object recognition tests where both recognition and habituation are measured by the same behavioural index – changes in exploration.
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These types of studies introduce qualitative changes in the exploration.
In addition, there were no significant changes in total exploration time.
Our data taken together provide evidence that the Comt1 B2isitselfelinkedked to the changes in object exploration.
That has begun to change: investment in exploration and production doubled between 2000 and 2006 (though much of the increase came through federal debt guarantees to private contractors).
As this review reveals, there is room for change in the exploration of patient-level data.
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