Sentence examples for changes in epigenetic from inspiring English sources

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Changes in epigenetic landscapes accompany the cell fate transition.

Genetic variations are comprised of structural and short polymorphisms and changes in epigenetic landscape.

Recent studies have shown that besides changes in transcriptome expression modifications in non-coding RNA species and changes in epigenetic events may also be involved.

Aberrant changes in epigenetic mechanisms such as DNA methylation, histone modifications and expression of micro RNAs play an important role in cancer and contribute to malignant transitions.

Aberrant DNA replication timing is associated with changes in gene expression, changes in epigenetic modifications and an increased frequency of structural rearrangements.

Changes in epigenetic patterns that occur as a result of human papillomavirus infection contribute to CIN progression to cancer, and can be harnessed to improve existing screening tests.

In parallel, activation initiates context-specific gene-expression programs that drive effector functions and cell fates that correlate with changes in epigenetic landscapes.

Differentiation of stem cells under various serum conditions to a committed state involves global changes in epigenetic patterns that are critically determined by chromatin modifications.

In summary, these experimental and clinical data suggest that changes in epigenetic programming are associated with neonatal lung damage by oxygen supplementation and BPD development but that there are inherent differences between the immature newborn and adult lung.

Interestingly, cancers and precursor cancer cells from lesions of advanced metastatic tumors also demonstrate this type of epigenetic drift, indicating that cancer progenitor cells hijack these age-related normal changes in epigenetic events in order to promote EMT for metastasis.

Indeed, it is well accepted that dynamic changes in epigenetic landscapes to control DNA accessibility and expression is a critical component during myogenesis for the effective repair of damaged muscle.

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