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Readily reversible changes in susceptibility may result from temporary phenotypic adaptations, such as the induction of stress responses (35, 36) and changes in envelope composition (37) or efflux pump expression (22, 38, 39).
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In order to investigate the relationship between the tremor phase at which each stimulation pulse was delivered and the changes in tremor envelope, we divided the percentage change in tremor envelope with respect to median tremor envelope amplitude observed during each recording block (Fig. 1F) into 21 bins depending on the corresponding tremor phase (Fig. 1E).
To investigate the relationship between the phase difference between beta activities in the STN and the globus pallidus, and changes in beta envelope, we divided the percentage change in beta envelope (with respect to the median beta amplitude envelope observed throughout the recording) into 20 bins depending on the corresponding phase difference between the STN and the globus pallidus (Fig. 1).
Regions within the gp120 subunit of the envelope protein interact with both CD4 and the coreceptor, causing conformational changes in the envelope protein.
The dengue envelope β-OG pocket is a crucial hinge for mediating virus-host fusion via conformational changes in the envelope to the fusion-competent form.
We sought to examine changes in HIV envelope sequences and inferred tropism in patients who did not respond to maraviroc-based regimens.
The signal used here is stable and exhibits only a few changes in its envelope for both the SE and SS methods, as shown in Figures 18, 19, and 20.
Compared with BK28, CP-MAC exhibited a number of changes in its envelope glycoproteins, including a highly stable association between the external (SU) and transmembrane (TM) molecules, a more rapid electrophoretic mobility of TM, and, of particular interest, a marked increase in the level of envelope protein expression on the surface of infected cells.
While Mtb not treated with THZ appeared to have normal envelope morphology (Figure 2A), those treated with either 1x (Figure 2B) or 4x (Figure 2C) dose of THZ for 6 hr exhibited discernable changes in the envelope morphology.
Subsequent binding of gp120 to CCR5 or CXCR4, which are members of the family of G protein-coupled, 7-transmembrane segment receptors, is thought to trigger additional conformational changes in the envelope glycoproteins.
HIV entry involves a stepwise series of interactions with receptors that initiate conformational changes in the envelope glycoproteins [ 12, 27].
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