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We are studying changes in developmental gene regulation during human evolution on multiple levels.
In many cases, release of dormancy results in increased cell division and changes in developmental programs.
We are exploiting these advances to identify human-specific changes in developmental gene regulation that contributed to human evolution.
Our laboratory uses a combination of computational and in vivo experimental approaches to study human-specific changes in developmental gene regulation.
The studies indicate that plant stress and consequent changes in developmental rate and nutritional quality of plants are playing a role in herbivore population responses to intercropping.
Furthermore, it follows that functional changes in developmental gene regulatory networks have to be considered as a primary mechanism for evolutionary process.
In many cases, the parasite employs aerobic metabolism during the free-living stage outside the host but undergoes major changes in developmental control and environmental adaptation to switch to anaerobic energy metabolism.
Although the effects of cadmium on aquatic insects have been studied in terms of their toxicity and changes in developmental parameters, little is known about its molecular and genetic effects.
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In Schistosoma, the change in developmental stage could result from the availability of choline, hampering its developmental cycle.
Recently, the discovery of strategies to reprogram somatic cells into induced pluripotent stem (iPS) cells has led to a major paradigm change in developmental and stem cell biology.
Just as development is a system property of the regulatory genome, causal explanation of evolutionary change in developmental process must be considered at a system level.
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