Sentence examples for changes in airway epithelial from inspiring English sources
Asthma, chronic obstructive pulmonary disease (COPD), and lung cancer are characterized by distinctive pathological changes in airway epithelial, SM, and mucous-generating cells.
Thus, it is well recognized that oxidative stress-induced changes in airway epithelial cells physiology plays a central role in innate and adaptive immune responses as well as mucosal inflammation [34].
Furthermore, they show that EMT during chronic inflammation not only drives phenotypic changes in airway epithelial cells, but also facilitates the migration of these cells to subepithelial regions of the airway wall.
In order to test this hypothesis, we then characterized serial chronological changes in airway epithelial cells and matrix components from the time of DA exposure to the development of BO.
We describe for the first time that Human rhinovirus infection causes DNA methylation changes in airway epithelial cells that differ between asthmatic and healthy subjects.
The change in airway epithelial structure was visualized by whole mount E-cadherin immunofluorescence staining (Fig. 9a).
In HEK293 cells, AP-2 is strictly required for efficient CFTR endocytosis, and the µ2 adaptin interacts directly with the CFTR YDSI motif in vitro.,, Thus, while a ~60% knockdown of µ2 adaptin caused no change in airway epithelial cells, a comparable 64% knockdown of α adaptin in HEK293 cells caused a 2-fold reduction in the endocytic uptake of CFTR.
We used diesel exhaust particles (DEP), the largest source of emitted airborne PM, to investigate pollutant-induced changes in miRNA expression in airway epithelial cells.
Moreover, expression of several genes in the AC1/AC2 signature appear consistent with reports about gene expression changes in relation to smoking in airway epithelial cells.
Ozone exposure in mice induces a persistent airway inflammatory response and emphysematous changes associated with an increased oxidative damage in airway epithelial cells.
These changes are associated with increased oxidative stress, inflammation and apoptosis in airway epithelial cells.
