Sentence examples for changes for functional from inspiring English sources
Recent studies reported that methylation mediated gene silencing was a common alternative to genetic changes for functional loss of these two genes in human tumors [ 18, 20, 23, 24].
The crystal structures along with analyses resulting in many new insights provide at least two major breakthroughs: the MutS ATP bound conformation and the requirement of the MutS conformational change for functional MutL interaction: together these provide an elegant regulatory mechanism for commitment to repair.
Limited available health resources mean the amount of therapy may be insufficient to drive neuroplastic changes necessary for functional improvements to occur.
Amino acid changes critical for functional divergence and acquisition of DXR-II biochemical activity were predicted, many of them corresponding to positions highly conserved in DXR-II, but otherwise variable in DLO1 and/or DLO2.
Despite an increasing assortment of immunological shifts recognized to occur with aging (Dorshkind & Swain, 2009), the specific changes responsible for functional immune senescence with ensuing infection susceptibility remain largely undefined.
The present analysis based on MGP identified expression changes for many functional categories, including proton transport and vesicle-mediated transport in the SI (Table 2) and immune responses in the LI (Table 1).
Change scores for functional outcomes are shown in Table 3.
These changes are responsible for functional alterations and for the accumulation of potentially injurious bioreactive substances.
Such changes provide targets for functional validation of molecular mechanisms of disease progression.
Between the first and the fourth courses of chemotherapy, patients reported a "moderate" change for 5 functional scales (difference of scores greater than 10 points) and they reported a large change for the role function scale (difference of scores greater than 20 points).
One intriguing possibility is that morphological changes like loss of gray matter provide one basis or substrate for functional changes in neuronal network architecture and communication.
