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The authors assessed the following clinical outcomes at 6-month follow-up: absolute changes (follow-up minus baseline) in A1C, weight, blood pressure, and lipids; relative changes (absolute change divided by baseline) in body weight; and the proportion of patients treated with liraglutide reaching A1C targets.
Change in coronary artery score was defined as the per-patient mean of MLD changes (follow-up minus baseline angiogram) (19, 20).
Furthermore, for monitoring functional infection outcomes like Salmonella colonisation, translocation and infection-induced permeability changes, follow-up of infected rats for at least 3 to 4 days is needed.
While most serious complications related to radiotherapy are relatively uncommon, given the number of patients that are treated and the relatively long latency period for development of radiation changes, follow-up imaging studies frequently have findings that should be recognized as radiation related.
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Whenever treatment of a patient is started, or changed, follow-up should either ensure that treatment is optimal or recognise that it is not and identify the change(s) in treatment needed.
To estimate lifetime cognitive change, follow-up cognitive scores were adjusted for baseline MHVS scores.
Furthermore, we calculated the descriptive characteristics of baseline BML volume and BML volume change (follow-up volume minus baseline volume).
To measure actual 4-year cognitive change, follow-up scores were adjusted for baseline scores on the respective cognitive test.
Therefore, for continuous outcomes, the effect size was the change (follow-up minus baseline) for each parameter in patients treated with PMX-F.
Group level "internal" responsiveness is analyzed using the "standardized response mean" (SRM) statistic ("efficiency" [ 37]), defined as the absolute value of mean change (follow-up minus baseline scores) divided by the SD of this change [ 21, 38].
Annual percentage change in cartilage volume was calculated by cartilage change (follow-up cartilage volume subtracted from initial cartilage volume) divided by initial cartilage volume and time between MRIs.
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