The other notable aspect was the changes were diametrically opposite in normal and cancer cell types.
Transcriptional responses partially reproduced in vivo signatures, but these microbes elicited diametrically opposite changes in expression of a neuronal-specific gene set, notably nociceptive neuropeptides.
A second conclusion is that, for 80% of the genes whose expression we studied, proactive and reactive fish showed quite distinct and sometimes diametrically opposite patterns of change in response to a LPS-induced inflammatory challenge.
When reminded at a news conference that she used to hold a diametrically opposite position on how to change term limits, she said that elected officials go off course if they "do not evolve" when circumstances change.
However – as was seen with anxiety – the effects of genetically-induced changes in 5-HTT activity on body weight were diametrically opposed to the effects of acute pharmacological manipulations.
The post-1960s New Left and, more recently, the anti-capitalist globalization movement shunned the nation-state as a strategic ally, arguing that it stood diametrically opposed to the interests of social change.
While CSF glutamate closely reflected changes in hemispheric water content, alterations in CSF taurine occurred diametrically to those seen for glutamate.
These two transcripts, however, showed diametrically opposed expression levels and very huge fold change which cannot be explained simply by means of an additivity model (Table 4).
This issue remains controversial as two recent studies reached diametrically opposite conclusions of clear HAART-related improvement versus no change [ 20, 21].
By explicitly counterposing geometry and topology in this series of experiments, we have demonstrated that hippocampal place cells show a remarkable degree of stability with respect to even dramatic geometrical changes in the environment: they retained their relative order and connectivity despite routes involving diametrically opposite protrusions and orientations.
