Sentence examples for changes culminating in from inspiring English sources

The Webley revolver went through a number of changes, culminating in the Mk VI, which was in production between 1915 and 1923.

With the arrival of the "beat" writers and artists of the 1950s and societal changes culminating in the Summer of Love in the Haight-Ashbury district during the 1960s, San Francisco became a center of liberal activism and of the counterculture that arose at that time.

Endothelial alterations often occur early in the disease, followed by vascular damage that leads to a cascade of stimulatory changes culminating in tissue fibrosis [4].

Comparable with the control joints, the medial knee compartment showed massive degenerative changes culminating in a complete loss of articular cartilage tissue and degeneration of the menisci.

When a mutation occurs and a longer polyQ stretch is present, the protein undergoes conformational changes, culminating in altered or even the loss of protein protein interactions.

As a cell divides, it undergoes massive shape changes, culminating in the formation of a small structure, the midbody, where cleavage between daughter cells occurs (Eggert et al., 2006b).

The changes culminated in 1985 with his formal resignation as head of the American Muslim Mission and his dissolution of the organization.

These changes culminated in George's 1999 arrangement, which had broad acceptance until 2005, when Austin Mast, Eric Jones and Shawn Havery published a phylogeny that did not accord with George's arrangement.

These changes culminate in progressive muscle wasting, with the majority of patients being wheelchair-bound in their early teens, succumbing to cardiac/respiratory failure in their twenties [ 12].

These neurobiological changes culminate in the development of spontaneous recurrent seizures (SRS) resulting from synaptic reorganization into hyperexcitable and hypersynchronous neural networks [ 4].

Without Ban's persistence, the world would never have made so much progress on climate change, culminating in the Paris agreement sealed in December 2015, DiCaprio said.