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Since EVT cell cultures increased their adhesion to FN, LN and VN upon treatment with LIF we reasoned that such changes could be exerted via transcriptional regulation of those integrin subunits that mediate the cell adhesion to these ECM elements.
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Power could be exerted to change or control the psychosocial environment in the paid work place when people were in a better bargaining position and/or had access to avenues to facilitate change (e.g. workplace policy or union representation).
This effect could be exerted close to the start of transcription mediated by chromatin changes on the promoter.
Until now, however, such control could be exerted only at the level of the entire organism.
Then again, perhaps control could be exerted by other kinases downstream of Cdk1?
Therefore, although the mechanisms responsible of this change with aging are unknown, the higher levels of RAC3 in young individuals could be exerting a senescence inhibitory role that then is lost.
This missing data could be exerting an effect on the utility scores.
Changes could be made.
Such changes could be made at once.
But some changes could be made immediately.
Change could be arbitrary.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com