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Landrieu argues that the programs, which includes Phase I and Phase II awards followed by commercialization, need to be monitored for several years before the impact of any changes can be assessed.
Cell cycle changes can be assessed in both in vitro and in vivo models.
These changes can be assessed by comparing the health of the patient before and after the cure.
Technological advances in the past 5 10 years have made large '-omics' experiments feasible, where biological changes can be assessed at the systems level.
If the considerations described above are taken into account, functional immune changes can be assessed in the human brain by using specific markers as detailed below.
In addition, by applying multimodal imaging, structural changes can be assessed with respect to changes in diffusion properties, susceptibility weighted imaging (SWI) and fluid attenuated inversion recovery (FLAIR) imaging.
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Land cover change can be assessed from ground measurements or remotely sensed data.
A complementary regional perspective of climate change can be assessed from internally drained lake basins, which are directly affected by insolation and precipitation balance.
Our findings are important because they suggest that land cover change, a key component of global change, can be assessed over large areas much further back in time than it is commonly done.
The approach used in this work has the potential to significantly improve the workflow as and when new products are introduced or modifications need to be made as the scope of change can be assessed rapidly resulting in more focused engineering and design work.
Therefore, by providing a more contemporaneous timeframe, the transformational impact of policy change can be assessed within a defined period (Donnelly and Hogan 2012).
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