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Similar to substitution alternative splicing, RNA editing causes amino acid changes by substituting individual nucleotides.
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First, people may respond to the price change by substituting the taxed unhealthy item with another unhealthy item that is not included in the policy.
Furthermore, in the absence of a consideration of possible protein conformational changes induced by substituting alanines in the active polyubiquitin binding sites of angiocidin, these results also suggest that residues I290 M294 play a more important role than residues L216 L220 in the binding of polyubiquitin and the induction of endothelial cell apoptosis.
We found that while geometry of some clusters change significantly by substituting of Al atom(s) with Si atom(s) the geometry of some others remain without significant variation.
In the case of raloxifene, removing the neutralizing change of the piperidine by substituting a cyclohexane resulted in increased estrogen-like actions, and moving the side chain of 4-OHT further away from Asp-351 also resulted in enhanced estrogen-like activity.
It would be a sin to throw that chance away by substituting cosmetic change for real reforms.
Weight loss is best achieved through increased physical activity and basic dietary changes, such as lowering total calorie intake by substituting fruits and vegetables for refined carbohydrates.
The steady-state solvatochromic studies show no appreciable change to the charge transfer of BMVC by substituting an anisole electron-donating group at 9-position of BMVC.
Entropy changes (ΔS) were calculated from the equation 5, by substituting the values of ΔG (eq. 3) and assuming a constant ΔH with temperature.
Hence, we reduce the endogeneity of the entry decision by substituting our measure of technical change with two alternatives.
The amino acid changes were designed to disrupt the salt bridge interactions by substituting a neutral alanine for a negatively charged aspartate or glutamate, or by substituting a negatively charged glutamate for a positively charged arginine.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com