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By themselves, both extreme prematurity and IUGR bear a similar risk for neurocognitive and behavioral impairment, and the here defined modular network alterations confirm similar structural changes both by IUGR and EP at school age compared to control.
For instance, A-928605 produced significant changes both by inhibiting early activation of molecules within the IGF signaling pathway and translationally that can be directly attributed to inhibition of IGF1R because none of these effects occurred in the vector control line.
The degree of crystallinity changes both by increasing the polymer concentration and solvent used for the film preparations.
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The Pleistocene/Holocene boundary at 11,650 cal yr BP is marked by changes both in vegetation composition and sediment type.
Within each set, the exit Reynolds number was changed both by varying the jet diameter and the fuel exit velocity of the flames.
An intermediate number of genes (340) were changed both by the loss of ATL9 expression and by chitin treatment (Figure 8B).
Every indication so far suggests that marine phytoplankton have the potential to evolve in response to global change, both by sorting standing variation in fitness and by using de novo mutation.
However, only one of these genes (PARK7) remained significantly changed (both by parametric and non-parametric approach) between hereditary and sporadic cases, when taking into account all probe sets present on the array.
Exposure to γ-radiation resulted in more extensive transcriptional changes classified both by the number of genes modulated and the magnitude of change.
The present landscape structure and function is the result of centuries of changes produced both by natural processes and human driving forces.
These SSNAPs have the potential to change both fields by stimulating new interdisciplinary courses and programs in numerous universities and by providing inspiring models of how to engage in cutting-edge scientific research on big questions of philosophy.
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