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Moreover, the positive change in the self-rated mood suggested that it might be a precursor for changing QOL, even over a limited time period before true QOL changes become apparent.
Moreover, the powerful long-term momentum that is built into the human age structure means that the effects of fertility changes become apparent only in the far future.
Biomarkers may provide diagnostic, prognostic, or burden of disease indicators of OA before radiographic changes become apparent.
The application of biomolecular magnetic resonance imaging becomes increasingly important in the context of early cartilage changes in degenerative and inflammatory joint disease before gross morphological changes become apparent.
However, prominent transcriptome changes become apparent after 8 hours of treatment, as highlighted by genes mapped to neurons in bottom-right corners (also termed Group 6 on the right panel of Figure 2A).
Hence, reasons for, and meaning of changes become apparent.
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A newfound willingness of legislators to consider such changes became apparent when bills to impose a two-year moratorium on executions passed committees in both houses, before eventually dying.
T2*-weighted (gradient-echo) hypointense signal changes became apparent at 24 48 h after transfusion, were typically associated with the ischemic lesion border, and could be followed up to 5 weeks after the insult.
In animals of advanced age (30 months) clear age-related changes became apparent, in which the enlargement of the print area of the hindpaws was the most prominent one.
In the albino Swiss mouse model of viral encephalitis, microglial activation revealed by tomato lectin histochemistry occurred relatively early during disease progression (8 dpi) when the first behavioral changes became apparent.
Eight days post-instillation (dpi), when behavioral changes became apparent, brains were fixed and processed to detect viral antigens, activated microglia, perineuronal nets, and T lymphocytes by immuno- or histochemical reactions.
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