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Patient function was measured pre-operatively, providing a baseline with which to compare post-operative function, but there was no independent assessment of possible longitudinal changes, assessed with a control group, nor was the assessment blinded.
This study shows that structural bone changes assessed with HR-pQCT are accompanied by alterations in systemic markers of bone resorption and bone formation.
Microstructural changes, assessed with DTI, are a potential marker of early white matter abnormalities in type 2 diabetes and may be more sensitive than classical MRI markers of small vessel disease.
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Trend analysis of experimental data reveals a general decrease of air pollution across the region, which agrees well with changes assessed by emission inventories.
In this process, the metabolite changes are assessed with respect to the strength of the change, the biochemical importance for a certain mode of action, and similarity of metabolite changes having biomarker character.
Correlations between patient-rated outcomes and longitudinal biomarker changes were assessed with Spearman's Rank Correlations.
Cerebral ischemic changes were assessed with diffusion weighted imaging (DWI) prior to and after angioplasty.
Structural changes were assessed with DWI three to one days prior to intervention as well as one day after angioplasty.
Gene expression changes are assessed with DNA microarrays and quantitative RT-PCR.
The morphological changes were assessed with mitochondrial volume (μm) as a variable.
The MMSE and AQT changes were assessed with the Wilcoxon matched-pairs signed ranks test.
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