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Increasing activity levels in everyday contexts can ensure that changes are integrated into everyday life and sustained over the longer term, stabilising functioning and improving ability to cope with future challenges to well-being.
In future work, it will be important to build from these findings to understand how this broad set of gene expression changes are integrated to promote formation of a normal sized compartment of cells.
Some may last beyond the resolution of tissue injury leading to chronic pain syndromes; a major conceptual and practical challenge for modern medicine, which requires a detailed understanding of how dynamic molecular changes are integrated into the cellular context of nociceptive processing in spinal and brain circuits (Kuner, 2010).
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These different changes were integrated in a numerical model, and in silico simulations supported the notion that chloride imbalance impair local inhibitory control of pyramidal neurons' activity in this model of MTLE.
These few but significant changes were integrated into the second edition.
These expression changes were integrated with our protein-protein interaction network and used to identify significantly altered genetic modules.
Gene expression changes were integrated with GO-Elite, GSEA, and Cytoscape to identify significant biological pathways and networks.
As for content validity, potential misunderstanding problems were mitigated during the expert committee evaluation stage and changes were integrated in the transcultural adaptation step, as previously discussed.
The gene changes were integrated into a Global Index of Dependence on Estrogen (GIDE), which enumerates the genes changing by at least twofold with therapy.
These changes were integrated into the paper encounter forms and into the MMRS data entry module, the latter by adding checkboxes and dropdown lists on prior care sought, tobacco use, symptoms, physical signs, and laboratory results.
Whilst the similarity in a development-related gene expression between different tissues was limited (Additional file 1: Table S1, Figure 6A) interactome analysis demonstrated that these changes were integrated into similar evolutionarily conserved growth pathways.
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