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While the changes are extensive, none were so drastic that it made the hotel unrecognizable; the hotel has retained its turn-of-the-century look and continues to feel more like an elegant apartment building than a hotel.
As in our example above of the different planning timeframes, where curriculum changes are extensive and may require review by a regulatory body, time to institute needed changes extends and is often perceived by employers as placing unacceptable constraints on their mandate to provide timely care for members of the community they serve.
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Transcriptional changes were extensive with more than 3000 genes showing a differential expression, with roughly similar numbers of these being up-regulated and down-regulated genes.
The axonal degeneration and mitochondrial changes were extensive and were observed both in subepidermal Remak Schwann cells and in small distal cutaneous nerves (Fig. 6B).
The number of ecological processes affected by climate change is extensive, including for processes operating at different times of year and across all life history stages.
Moreover, data gaps are particularly in developing countries, which sometimes lack consistent data collection and sharing frameworks, yet where land systems change is extensive.
Those changes, which are extensive, are probably influenced by temperature.
When cystic changes and haemorrhage are extensive, oncocytomas may present as a hypovascular mass (Fig. 5).
The evolutionary advantages of being able to rapidly change jaw size are extensive, since such adjustments will produce substantial differences in the biomechanics of fish feeding that will result in important shifts in trophic ecology [21], [33] [35], [86] [90].
The nearly universal switch (97%) in Bangladesh since 1971 from using surface water for drinking to tube-well water has shown that water use traditions can be changed, provided there are extensive community education programs and support from both the government and nongovernmental organizations (WHO 2000).
The agency has not said precisely how the rules will be revised, but F.A.A. officials said the changes would cost the industry about $165 million over the next 10 years, or several thousand dollars per aircraft, suggesting that the changes are not extensive.
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