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On breast tissue sections, histological apocrine changes are defined by eosinophilic cytoplasms with fine granularity, large nuclei with occasional large nucleoli and frequent apical snouts [ 21, 22].
The majority of these changes are defined by medical specialists in committees organized by official agencies, professional organizations, and international institutions, like the World Health Organization (WHO).
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The interevent time for formation changes was defined by (tau^{k}_{i} = t^{k}_{i}-t^{k}_{i-1}) ((1le ile N_{k})).
Anatomical localization of the cerebral areas showing GM changes was defined by an experienced observer, using the Talairach Daemon.
The dR/dC ratio was calculated using the Zhang method [ 77], for which radical and conservative amino acid changes were defined by the Dayhoff classes ("AGPST", "DENQ", "HKR", "ILMV", "FWY", and "C").
Given the seven-month duration of the feeding paradigm, the effect of the J147 diet could only be assessed in old SAMP8 mice, and age-related changes were defined by comparison to the young SAMP8 animals.
This question is very important from theoretical and practical viewpoints, because delay differential equations arise in many applied problems when describing the processes whose rates of change are defined by present and previous states (for example, see [12 14] and the bibliography therein).
Pixel-level change was defined by the slope of the linear regression between fractional woody cover and year.
Proteins for which the levels significantly changed were defined by comparison between glucose and each polysaccharide (xylan, galactomannan, and pectin) at these thresholds.
A clinically significant change was defined by a change in category; the different categories are defined as follows: normal (0 6), mild (7 10), moderate (11 13), severe (14 and above).
Change was defined by adjusting for the baseline scores of the EQ-5Dindex [ 22]; in this way, regression to the mean was corrected simultaneously.
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