Sentence examples for changes and phosphorylation from inspiring English sources

Our aims were at first to determinate expression profile of GSK3ß and its regulatory genes (Wnt ligands 1, 3a, 5a, Frizzled Receptor 1 and 2, sFRP-1 and Axin1) and quantify protein level changes and phosphorylation status in MCT-induced PAH rat lungs and in isolated PASMCs.

It allowed us to perform double or triple labeling for immunofluorescence microscopy and thus to determine the sequence of phosphorylation on each site in the same cell and with exact knowledge of the stage of the cell cycle by monitoring DNA morphological changes and phosphorylation of Histone H3.

Key steps in amino acid-induced Ssy5 activation include amino acid-induced conformational changes and phosphorylation-induced ubiquitination by the combined activity of the casein kinases, Yck1,2 and the SCFGrr1 ubiquitin ligase complex, the latter targeting the pro-domain for proteasomal degradation (Abdel-Sater et al., 2004, 2011; Omnus et al., 2011).

Signalling is initiated, when active RAS recruits RAF to the plasma membrane for activation through a complex process requiring lipid and protein binding, conformational changes, and regulatory phosphorylation and dephosphorylation events.

These results show that cold stress of the basal parts of rice leaf sheaths changes the glycosylation and phosphorylation profiles of calreticulin, a key protein that regulates the quality control of other proteins [33].

The EDL and myocardium removed from these animals were used exclusively for the investigation of changes in protein and phosphorylation levels of translation initiation signalling events.

However, no significant changes of expression and phosphorylation levels of p38 and JNK were observed after icaritin treatment (Fig. 6B & C).

Changes in expression and phosphorylation of target receptors were detected using western blot.

The KINEX microarray, however, allows to analyze only changes in expression and phosphorylation levels of LIMK1.

These changes in cytokine and phosphorylation profile of MSC led to increased chemoresistance and stemness of breast cancer cells.

We also explored the changes in expression and phosphorylation or activation of several relevant proteins following experimental elevation or knockdown of RRIG1 expression in breast cancer cells.