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To investigate the factors giving rise to design changes, a total of 43 causes were first identified through a comprehensive literature review.
This resulted in the insertion of 2934 bases and an additional 42 base changes, a total of 2976 corrections in a final chromosomal assembly of 7898767 bases (0.03768 %).
According to sample size calculations (significance level 5%, power 80%), assuming that one third of the acute WAD1-2 patients would show ligament high-signal changes, a total of 100 responders at 12 months follow-up would be needed to detect a difference in proportions recovered from 60% in those without ligament changes to 30% in those with ligament changes as statistically significant.
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The words "change" and "changes" appear a total of fourteen times.
Concerning fold change, a total of 1864 genes had > 2-fold change in either direction (1098 up- and 766 down-regulated).
Using a cutoff of ≥2-fold change, a total of 250 H2O2-sensitive genes were identified (P<0.01), 39% (97/250) of which were not modified by the presence or absence of PIAS1 (Fig. 4 A, left panel).
Mr Miliband said an impact assessment suggested 420,000 disabled people faced losing £700 a year as a result of the changes - a total of £306m - while the hardship fund covering those affected had an allocation of just £25m for disabled people.
Zinke in September proposed changes for a total of 10 national monuments, and the outcome of the full review is expected soon.
Many of them listed several changes, for a total of 178 comments.
In this case, three out of the nine paleoAP3 amino acids are changed before the frameshift and three of the ten euAP3 amino acids are changed afterward (a total of four of these changes are chemically non-conservative).
TfL's plans, which they say are subject to change, show a total of 216 stations could have their staffing numbers cut from January 2015, with about 588 staff due to be shed in total across the network.
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CEO of Professional Science Editing for Scientists @ prosciediting.com