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It is easy to see how this type of interaction could become destabilizing when the tBu substituents are changed to larger solubilizing groups.
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During 8 6 ka BP small drainages changed to large lakes and extensive deposition of sediment took place in the upland interfluve surfaces.
"Public opinion has changed to a large extent, though certainly not completely," he told VICE.
During the past two decades the operative management of cancer has changed to a large extent.
When the nature of the questions changed to address a larger issue -- was he falling apart?
A wider spread will occur if the threshold is changed to give a larger PFA.
The change to larger guns was prompted by the Japanese s, which also mounted eight 16-inch guns.
They should consider implementing changes to larger sites in stages.
Allosteric communication in myosin V: from small conformational changes to large directed movements.
Or if rapid changes to large numbers of files trigger an alert, ransomware could tick away slowly and patiently.
The modifications can range from single base changes to large insertions or deletions and leave no operational sequences.
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CEO of Professional Science Editing for Scientists @ prosciediting.com