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Discover Ludwig"changed profoundly" is correct and can be used in written English.
For example: After the passage of the new law, the economy has been profoundly changed.
Exact(60)
Has anything changed profoundly?
It has changed profoundly.
The politics have changed profoundly.
But capitalist economies changed profoundly too.
However, this static picture has changed profoundly.
The political landscape has also changed profoundly.
This has changed profoundly over the last 15 years.
By the mid-'70s, publishing had changed profoundly.
While society changed profoundly, however, political processes did not.
In most other ways he has changed profoundly.
Mr. Kessel said the energy market had changed profoundly.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com