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For example, when the cytosolic protein IDE (insulin degrading enzyme) was engineered to relocalize to the mitochondria, it immediately changed its function from regulating plasma insulin levels to degrading peptides (Leissring et al. 2004).
But if after RF shift the protein has changed its function, then it is of great interest to understand how changes in amino acid sequence determine the protein's new function.
"The building has changed its function," says de Vaux.
This indicated that one of the members changed its function during the course of evolution.
One of these receptors (Dappu_InR-4) has likely changed its function but does not appear to be under positive selection.
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When the form of a protein changes, it can often change its function, how it will interact or where it ends up in a cell, said Bordeleau.
"If Facebook wanted to enter China, it would not have to change its function, because netizens here are used to copycats already, but it must, like other international internet companies, obey Chinese laws and regulations," said Hu Yong, a professor at Beijing University's school of journalism and communication.
The finding suggests that the visual cortex can dramatically change its function — from visual processing to language — and it also appears to overturn the idea that language processing can only occur in highly specialized brain regions that are genetically programmed for language tasks.
This is surely more conservative than the explanation that the mirror changes its function when he is in front of it.
Interface design tools allow a mobile app or a website to change its function or appearance, depending on where a customer is in his or her journey.
They will build the device from stem cells and learn how to power and image it, as well as how to measure and computationally model the way drugs, microbes, and immune cells change its function.
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