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Another influence, several said, was a group of Egyptian expatriates in their 30s who set up an organization in Qatar called the Academy of Change, which promotes ideas drawn in part on Mr. Sharp's work.
"The system's response when there's a problem or an outcry about something is always to appoint one person in central office or one person in each area to take care of it," said Donald Moore, executive director of Designs for Change, which promotes community engagement in educational policy.
Upon binding a ligand, PPARα undergoes a conformational change which promotes the formation of a cofactor binding pocket, subsequently allowing interaction with the so-called LxxLL motif within some coregulators.
AMP binding results in a conformational change which promotes Thr 172 phosphorylation by upstream kinases, including tumor suppressor liver kinase B1 and the Ca2+/calmodulin-dependent kinase (CamKKβ) and prevents its dephosphorylation by protein phosphatases.
ApoE does not bind to the LDLr family in its lipid-free state, as interaction with lipid is necessary to induce a conformational change which promotes high affinity for the receptors [39].
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Nevertheless, the plant seems well tolerated in many genomic groups by combining traits from two parental species and even potentially benefits from those changes, which promotes growth vigor in response to "genomic shock" stress in their hybrids (McClintock 1984; Paun et al. 2007; Ungerer and Kawakami 2013).
We conclude that active site ligand binding events themselves are responsible for conformational changes which promote enzyme-enzyme association of OTCase with arginase.
Nitrated apoB-100 showed profound conformational changes, which promoted increased LDL binding and uptake by endothelial cells.
Our results provide detailed insights into the changes that occur in bacteria in response to life cycle changes, which promote infection and pathogenicity.
Fundamental research strongly suggests that tumour cell sensitivity to genotoxic damage is induced by oncogenic changes which promote apoptosis (Lowe and Lin, 2000).
These neural alterations may be attributed to obesity-related metabolic changes, which promote food craving and high-calorie food (HCF) consumption.
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