Sentence examples for change the specificity of from inspiring English sources

Yet that scrawling out of Napoleon's name doesn't change the specificity of Beethoven's inspiration in writing this symphony, the longest and largest-scale he had ever been composed, and the profound human, philosophical, and political motivations behind the musical innovations of this jaw-dropping piece.

The ability to change the specificity of the antibodies will enable the biosensor to be used as a detection device for other types of foodborne pathogens.

Mutations in protein interaction sites in c-Myb lead to defects in hematopoietic stem cell differentiation [11], and change the specificity of c-Myb, allowing it to regulate different sets of target genes [2], [3], [12].

These observed features provided a clue that CrSPI-1-D1 might specifically target thrombin after modifications of a few residues in the RSL, and this prompted us to change the specificity of CrSPI-1-D1 targetgethrombinin.

Gillian Murphy (Cambridge, UK) has used mutational analysis to change the specificity of the different TIMPs.

Phosphorylation of PhoP increases the affinity but does not change the specificity of DNA binding.

Especially remarkable is the finding of Bojunga et al that changing the number of PCR cycles in analysis completely changes the specificity of Tg-mRNA detection.

Thus, we have changed the specificity of the FHA1 domain and demonstrated that engineering phosphopeptide-binding domains is an attractive avenue for generating new anti-phosphopeptide binding specificities in vitro by phage display.

We did apply our scoring function to the experiments by Skerker et al. [20] who changed the specificity of the E. coli kinase EnvZ from its native RR partner OmpR to RR RstA by a set of four subsequent substitutions.

Binding of thrombin to thrombomodulin also changes the specificity of thrombin from a procoagulant to an anticoagulant enzyme [ 2].

Hybridization is an alternative to directed evolution that has successfully changed the specificity of several small serine recombinases.