Sentence examples for change of histone from inspiring English sources

Thus, the ratio of AcH3/H3 or AcH4/H4 accurately reflects the change of histone acetylation.

We first used an antibody against acetylated histone H3 to detect the change of histone H3 acetylation level at the RTA promoter.

For example, the dynamic change of histone acetylation and deacetylation has been shown to drive the spliceosome assembly and rearrangement [ 32].

They may modify chromatin by inhibition of histone deacetylases without significant change of histone deacetylase transcription, thus their target genes do not necessarily occur in microarray studies as differentially expressed genes or at the top of a list of these.

The change of histone methylation affects the efficiency of gene expression at several levels, including methylation of the promoters, cap formation, the stability and export of mRNA, and the initiation of translocation.

However, the recent characterization of histone mark distribution on tissue specific genes was carried out in matured tissue cells, little is known about the dynamic change of histone modification during the cell differentiation and development, neither is it known that at what developmental stage the H3K4me2 marking is acquired.

Acetylation-mediated change in the charge of histone tails is thought to weaken histone-DNA contact (5), modulate histone-histone interaction between adjacent nucleosomes (71), and affect interaction between histones and regulatory proteins (33).

These data nicely demonstrate the dynamic and reversible changes of histone H3K4 methylation and H3 acetylation in responses to environmental changes in rice.

Glycolysis provides energy for growing lymph vessels, while fatty acid oxidation is a critical metabolic regulator of lymphangiogenesis, in part by promoting nucleotide synthesis as well as by mediating epigenetic changes of histone acetylation, which promotes transcription of key lymphatic genes, and hence venous-to-lymphatic endothelial cell differentiation.

For example, the first genome wide characterization of epi-toxicogenomic changes of histone acetylation profiles at a thirty five nucleotide resolution using Affymetrix Promoter Tiling arrays was reported [39].

These changes of histone acetylation allow chromatin open structure to recruit repressor binding to the hTERT 5'-regulatory region [15], [19].