Sentence examples for change of functionality from inspiring English sources

Firstly, there should be vigilance to the possibility of an evolution or change of functionality of pNETs, during tumour progression, particularly in non-functional pNETs considering their pluripotency with awareness of the various clinical syndromes that may arise.

One change of functionality within the TRP-N family was the shift from the pull to a push mechanism (see Introduction).

In both cases this has resulted in a change of functionality (i.e. amino acid activated) and subsequent production of microcystin-RR.

112 Given that changes of functionality and a decreased number of stem cells contribute to or accelerate aging, implantation of stem cells to replenish new functional stem cells would be one means to attenuate age-associated disease by rebuilding the tissue or organ.

The sleep wake disturbances in elderly people and particularly in patients with Alzheimer's disease may result from changes at different levels: a reduction of environmental synchronizers or their perception, a lack of mental and physical activity, an age or disease related anatomical change with loss of functionality of the biological clock.

However, for individual branches it is in principle still possible that the loss of constraint occurred very recently, and that while missense mutations led to a change or loss of functionality as demonstrated in other GPCR [35], ORF disruptions have by chance not yet occurred.

In this study, thus, a hypothesis was tested that the modulation of the cytoskeletal structure of cells embedded in the extracellular matrix (ECM) can mitigate the freezing-induced changes of the functionality and can reduce the amount of CPA necessary to preserve the functionality of ETs during cryopreservation.

This kind of modeling extremely simplifies the specification of processes that have to operate in dynamic environments, since the developer does not need to think about and specify all the possible alternatives to deal with specific situations (e.g., context changes, availability of functionalities, improbable events).

The reduction of viable bacteria counts in the case of the ALG@180 systems can be attributed to heat injuries induced during oven film drying and not with changes of the functionality of sodium alginate under the acidic conditions.

However, early changes of synaptic functionality might contribute to early stages of the metabolic switch, which in turn could contribute to further NMJ changes and a self-propagating process.

However, recent insights into pathological changes of RBC functionality and integrity during storage - collectively known as the storage lesion - has drawn attention to the potential negative consequences of pRBC transfusion as it limits the post-transfusion survival of RBCs in vivo [ 3].