Sentence examples for change of efficacy from inspiring English sources

Under the assumption that the repeated measures across subjects follow a trivariate distribution whose mean and covariance matrix exist, the DM efficacy hypothesis is formulated by comparing the change of efficacy outcome between treatment arms with and without a treatment switch.

Comparisons between GFT505 and placebo were computed using relative change of efficacy parameters as the explained variable, group as the explaining variable, and baseline values as the covariate.

General linear model by repeated measure ANOVA was generated to assess changes of efficacy variables from baseline at 30 and 90 days.

Basal binding and UK14304, 8-OH-DPAT, and baclofen potency to stimulate [35S]GTPγS binding decreased with aging (1 88 years) without changes of efficacy.

Although removal of AA-containing herbs from the formulae is necessary, any modification should be carefully studied in order to avoid changes of efficacy.

FMI can be used to monitor changes of tumor before and after treatment of a certain drug, as well as changes of efficacy in response to dose changes of drugs.

The promoter is from the plant gene OPTX and augmentation of the promoter reporter with cGMP and GA response elements resulted in changes of efficacy in the different cell types.

Conversely, while tetanic activation of cortical fibers showed significant LTD of the FP amplitude in WT animals, in PrPmtA and PrPmtB mice the FP did not show any long term change of synaptic efficacy (Fig. 6D). Figure 6C shows traces obtained from three single experiments recorded from slices prepared from representative PrPmtA, PrPmtB and WT mice.

A change in the target population, however, can cause a change of the efficacy parameter.

The change of drug efficacy was reflected by an increase in the total amount of doxorubicin present in the cell at equitoxic (IC50) concentrations.

Important study amendments included premature termination of the trial owing to slow recruitment and change of primary efficacy variable to response based on Investigator's Global Assessment (IGA) instead of overall scaling score.