Sentence examples for change of affinity from inspiring English sources

The change of affinity results from compromised selection of high affinity antibodies within the germinal center [ 19, 20].

Next, we tested how the receptor mutations change binding to IFN- γ and these ΔΔ G gauge the change of affinity.

However, greater flexibility of L2 in the complex, permitted by the mutation, might make this change rather neutral resulting in only a small change of affinity, as is observed.

A possible but also not necessarily more precise alternative to judge indirect effects on drug binding would be to run free energy simulations with the bound drug to judge changes of affinity caused by the mutations but this is a tricky and time-consuming endeavour that would burst the scope of this current manuscript.

The explanation could be that diminishing the basic character of the terminal amino group may result in a change of its affinity towards the zinc ions.

It is plausible that a change of TCR affinity will not influence the extent of CD8 engagement with MHC class I molecules while a variation of epitope density will.

As shown in Figure S5 in the Supporting Information, as pH changed, the change of PDI affinity between ssDNA and dsDNA was negligible.

The triggered change of the affinity of the ionophore, the charge of the ion exchanger, or the p Ka of the indicator will suddenly allow for a controlled change in sensor characteristics in space and time.

Indeed, conformational changes linked to immobilization of an antibody can lead to steric hindrance or the alteration of the paratope region and therefore to a change of its affinity for the antigen.

In order to find the affected transcription factors and quantitatively measure the change of binding affinity, we used motifs of different transcription factors from Jasper [ 50] to scan the surrounding sequences of the above two genetic variants in a different allele state.

To conclude both experiments above (Fig.  5), it can be stated that an electrolyte buffer modification does change affinity of NCs to a micellar plug, which regulates the NCs release from micellar to micelle-free zone.