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Pre- or immediate adaptation of male moths to such sudden changes is critical for emergence of a population using novel pheromone blends, and it is unlikely that a great change in the specificity of pheromone receptors is caused by mutations at the same time as those in the pheromone biosynthesis pathway.
Among animals, however, trnI(cau) has been found only in sponges and placozoans, whereas it has been lost in bilaterians in parallel with a change in the specificity of the ATA codon from isoleucine to methionine (Lavrov 2007).
The clade II enzyme provides an example of the development of a neofunctional gene for which the substrate, the egg envelope protein, has adapted to a gradual change in the specificity of the corresponding enzyme.
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Even small changes in the specificity of the detection method may have a large impact on the likelihood of a true outbreak.
We sought to characterize changes in the specificity of alarms produced by standard time series outbreak detection methods as a function of time.
We used functional magnetic resonance imaging (fMRI) to investigate developmental changes in the specificity of the neural response to speech compared to biological non-speech sounds.
Jensen in 1976 pointed out the importance of "recruitment" of new enzymes in evolution by gene duplication followed by changes in the specificity of the new copies so as to take on a related, but new role [ 10].
Changes in the specificity of CATT and CATT titration, cost of pentamidine, and HAT prevalence decreased the difference in the cost-effectiveness ratio with the next most efficient algorithm.
The distribution of functional gene classes between leaderless and Shine-Dalgarno transcriptomes suggests that changes in the specificity of translation may play a role in bacterial adaptation during infection.
Therefore, for the protein protein interaction plots, the large coverage i.e. diversity of sites being exploited by different relatives, could be associated with changes in the specificity of the proteins that they bind.
GOF mechanisms may be the result of changes in the specificity of the DNA-binding activity of the p53 mutant, leading to the induction of novel transcriptional programs, or changes of its interaction with other cellular proteins directly or indirectly related to the regulation of gene expression.
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