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The AFM results suggest that the killing of bacterial cells by DC is not through direct physical forces of the currents (no change in the integrity of cells), but the electrochemical factors may play important roles.
In vitro, the TEER change reflects a change in the integrity of epithelial cell tight junctions since the TEER is primarily determined by the apical tight junctions.
Further histological analysis revealed no change in the integrity of the spinal cord following V1 IN ablation nor was there any reduction in neuronal cell numbers.
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The proposed Torrent air-permeability method also can be used to identify such changes in the integrity of concrete.
Within the framework of relating changes of measured modal parameters to changes in the integrity of the structure, it is important to be able to determine the dynamic stiffness in each section of the structure from measured modal characteristics.
Nonetheless, when the effect of the field (~0.1 T) is combined with that of SPION, more adverse changes in the integrity of cancer U937 cells can be induced, when compared to normal peripheral blood mononuclear cells, which are associated to the diamagnetic nature of the biological cells [60].
The Golgi fragmentation phenotype that we observe is distinct from that seen with nocodazole treatment in that the fragments are larger and do not become scattered throughout the cytoplasm, in addition we observe no changes in the integrity of the microtubule cytoskeleton following BIG1 suppression.
The results of TEM have qualitatively shown the changes in the integrity of the TJ barrier after GTPs treatment.
Thrombus formation and occlusion of the artery appear to be caused by changes in the integrity of the vessel wall induced by the presence of the catheter [ 79].
Effective concentrations of the bacterial toxins were prior titrated by visualising changes in the integrity of the cytoskeleton via FITC-phalloidin staining (see addional file 6A).
Accordingly, the ANP-induced increase in vascular permeability described in vivo might be related to changes in the integrity of the glycocalyx.
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