Exact(44)
A well-documented phenomenon involving a strong change in synaptic latency is 'delayed release', also called 'asynchronous release', where release extends for 10 s of ms to 10 s of s following the end of an AP train26.
Cortical spreading depolarization (CSD) is a spreading loss of ion homeostasis, altered vascular response, change in synaptic architecture, and subsequent depression in electrical activity following an inciting neurological injury.
As reducing Synj phosphorylation and activity in mnb1 is not physiologically equivalent to an actual loss of Synj protein, the synaptic morphology of mnb1 was different from synj-null mutants (reported to show either hyperbudding or no change in synaptic morphology)30,63.
Since we neither observed a change in synaptic strength nor morphological changes in the active zone we conclude that the observed reductions in presynaptic proteins do not underlie or at least are not sufficient41 to cause the observed changes in synaptic transmission in SPLfl/fl/Nesmice.
b The change in synaptic conductance stemming from low frequency stimulation, yielding LTD.
The change in synaptic strength due to the plasticity means that the PRCs of the neurons also change.
Similar(16)
mnb1/Df showed the most striking changes in synaptic morphology.
Perhaps long-term alterations of EEG dynamics were due to changes in synaptic short-term plasticity.
But it turned out that the phosphorylation mechanism was the key event in slow synaptic transmission, the changes in synaptic strength that lasted over many hours or days.
Here, we study postnatal changes in synaptic ultrastructure and exocytosis in a calyx-type nerve terminal.
Such declines may involve altered neuroplasticity, due to changes in synaptic function and neurotransmission.
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