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Whereas the primitive power of a substance is the efficient cause a post-Humean might say the real cause of the change of its perceptual states, these states themselves function as the teleological or final causes of change in substances.
But, as we have already seen, Leibniz rejects the view that God alone is the real causal power driving change in substances; apart from some rare Malebranchian moments, he is no occasionalist (Notes on a Reply of Foucher, G i 373f/L 155).
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He dismissed the statement as "a change of tone…but not a change in substance".
Abuse of prescription and over-the-counter medications represents the single most significant change in substance abuse trends in recent memory.
The Report of the President's Committee to Revise the Nationality Laws (1939) indicates this change in language was not regarded as a change in substance, p. 23.
Of the 18, 13 caudate-putamen sectors showed a significant change in substance P expression after administration of 5 mg/kg methylphenidate (Figures 4 and 7, Table 2b).
It's to be hoped a change in tone might signal a change in substance, but still, Tatchell's cynicism is not unfounded.
Still, advisers to the Democratic candidate believe that even a change of tone, with a limited change in substance, will have a dramatic effect on the nation's international standing.
Brown, who will not set out detailed policy plans at his campaign launch, will signal a major change in substance once he takes office by burying one of the most controversial aspects of Blair's 'sofa' style of government.
Given the setting in which the comments were made, Congress' awareness that the language of § 1979 had been altered indicates its understanding that no change in substance had been effected.
When baseline period was compared to the period after randomization and before treatment, the change in substance use was substantial (dropping from an average of substance use on 30.5% of days during baseline to 16.7% of days during the pre-treatment phase; p < .001), and was greater in magnitude than change following initiation of study-related treatment.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com