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While ECFCs adhesion and proliferation increased with substrate stiffness, no change in phenotype was observed.
One economically important example of a change in phenotype due to a PAV is the altering of pungency, or spiciness, in pepper.
They found that TGF-beta and interleukin-8 are specific tumor-secreted factors that contribute to the stem cells' eventual change in phenotype to myofibroblasts.
If the expansion phase is considered to result in a change in phenotype towards a proliferative nonprotein secreting cell, the differentiation phase is the opposite.
This change in phenotype is characterized by a raised expression of type I collagen and a decrease in type II collagen expression.
During the humoral immune response, B cells undergo a dramatic change in phenotype to enable antibody affinity maturation in germinal centers (GCs).
Although no outward change in phenotype was apparent, we characterized the molecular phenotype through integrated analysis of transcriptome and metabolome profiling.
Note that this change in phenotype was not due to pollution making the moths darker.
Such a connection is required to be able to identify how a specific mutation gives rise to a specific change in phenotype.
In its presence, these cells undergo a dramatic change in phenotype whereby they acquire most of the characteristic properties of sympathetic neurons.
In organs that exhibited no significant change in phenotype in the Srs5 mutant, these alpha-tubulins might work redundantly to maintain rice body planning.
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