Sentence examples for change in modification from inspiring English sources

We also confirmed our mass spectrometry data that RanGAP1 and PML are basally SUMOylated but largely do not change in modification status following IAV infection, whereas TRIM28 is highly deSUMOylated during infection.

This implies that a primary role of these proteins is to co-ordinate changes in modification status at their target sites.

ChIP assays were done with antibodies to specific acetylated or methylated amino acid residues and changes in modification at NucB on the MMTV promoter were determined.

Numerous changes in modification patterns have also been observed at the level of posttranslational histone modifications [109].

Increased expression and changes in modification(s) were observed for LRAG, a protein involved in granulocytic and neutrophil differentiation, and angiogenesis.

An interesting open question for the future is whether the gradual change from H3K36me3 to H3K27me3 observed at the nucleation region during cold exposure involves progressive, gradual changes in modification levels of the different histone tails in all cells.

While cancers have atypical patterns of histone modifications, none of the locus-specific changes in histone modifications has so far been related correlatively or causally to clinical outcome.

This direct approach reveals how specific histone modifications change before and after drug exposure and how these changes in histone modifications correlate with altered gene expression [ 31, 32].

The highly reproducible changes in tRNA-modification spectra demonstrate that the exposures promote reprogramming of the system of RNA modifications, which has been referred to as the ribonucleome.

The histone modifications reported in our study also support the clinical impact of genome-wide changes in epigenetic modifications in rectal cancer patients.

Variable-temperature experiments demonstrate both crystallization effects and changes in the modifications.