Sentence examples for change in alternative from inspiring English sources

We focused on a core set of RefSeq entries (20,157) with p-values of less than 0.05, and used the DE value plotted against the AS score to evaluate the relationship between expression and change in alternative splicing.

This phenotype is similar to those reported by Gallagher et al. upon RBFOX1/2 knockdemonstratingsthatinhibitionnhibitiof of the RNA binding properties of RBFOX1/2 proteins by the decoy oligonucleotides and the concomitant change in alternative splicing, result in a delayed muscle development phenotype in vivo.

Nine other previously identified cardiac targets showed no significant change in alternative splicing in Myo-CELFΔ-370 muscle (Table 1).

This early change in alternative splicing was not seen for LDLR exon 4 or 12 skipping, or for MVK exon 4 skipping (data not shown).

Only some of the transcripts that were previously identified as being targets of CELF-mediated alternative splicing regulation in the heart [4], [21] showed a demonstrable change in alternative splicing in Myo-CELFΔ muscle (Figure 2 and Table 1).

Next, we performed a detailed analysis of chromatin marks along the FN1 gene including the EDA exon where we did not detect any change in alternative splicing after NaB treatment.

Furthermore, if the FCA/FY interaction does indeed become less stable with increasing polyglutamine length, then changes in alternative splicing of mint FCA-like RNA [ 22] might be detectable in vivo.

The vast majority of multi-exon genes in higher eukaryotes are alternatively spliced and changes in alternative splicing (AS) can impact gene function or cause disease.

The biological consequences of seizure-related changes in alternative splicing of Kcnma1 deserve additional investigation.

Complex changes in alternative pre-mRNA splicing play a central role in the epithelial-to-mesenchymal transition (EMT).

We observed changes in alternative splicing of four muscle related RBFOX targets17 in RNA isolated from the larvae derived from the RBFOXi injected fertilized eggs (Fig. 4b).