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"There has to be change, big change.
Others carry the theme "Small change, big difference".
"Male, pale and stale Westminster needs to change big time".
"The church is in the business of change, big time: change of human heart.
I would not change Big Phil's preferred XI, not even Júlio César in goal.
But I did it because I knew that this country needed a fundamental change, big change.
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Significantly expressed RNAs have a fold change bigger than two with a FDR smaller than 0.1.
As you get more comfortable, change bigger things.
It means making changes, big and small.
The strategy required brings changes;and big changes upset people.
To detect small changes, bigger cohort sizes might be necessary.
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