Statistical analysis simulating random samples confirms that the degree of statistical difference between control and GM NK603 corn treatment groups can arise by chance (Table 1).
Strikingly, individuals in unusually good condition were also predated more frequently than expected by chance (Table 4).
Three pathways, EGF receptor, adipogenesis and TGFβ receptor, were identified in which genes occurred at a higher frequency than they would by chance (Table 2b).
Indeed, only a small percentage of cancer genes coincided with polymorphic CNVs and this percentage is even smaller than expected by chance (Table 2).
We analysed the data further using Pathway Express software and identified 18 KEGG pathways unlikely to occur on this probe list by chance (Table S3).
The highest uni-modal classification accuracy was obtained in aud L; aud R, S2 L, S2R, preM L, preM R, and S1 L, could also classify significantly above chance (Table 3).
A survey of the annotated functional categories [36] of EHR genes reveals that a dominant feature of this gene list is the large percentage of putative regulatory proteins, more than double the number expected by chance (Table 2).
In the GWAS study of Harold et al. [7] involving approximately 12,000 AD cases and controls, we observed a considerable excess of SNPs surpassing different thresholds of significance when compared with those expected by chance (Table 1), suggesting the existence of many LOAD susceptibility loci that were not detected at genome-wide significance.
By the least stringent definition of a seed match – a six-nucleotide match complementary to nucleotides (nt) 2 7 or nt 3 8 in the miRNA – 70% of the miR-1 targets and 75% of the miR-124 targets possessed seed matches, a highly significant (P<10−6 and <10−25, hypergeometric density distribution) enrichment over would be expected by chance (Table 1, designated '6mer' seed match).
For inter- and intra-observer reliability, some ratings showed "perfect" agreement beyond chance (Table 3).
