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And mothers who do not breastfeed increase their chances of type 2 diabetes, as well as breast and ovarian cancer.
Studies in mice have found that large doses of the appetite-controlling hormone leptin during infancy permanently prevent excess weight gain and reduce the chances of type 2 diabetes.
To further account for the fact that including many predictors in the models could increase the chances of type I error (false positives), we also estimated adjusted p-values for the terms in these full models following the Benjamini Hochberg procedure75 to detect false discovery rates (FDR).
Inclusion of other ratios for performance assessment of semi-quantification (such as right to left ratio and caudate to putamen ratio) is likely to increase the chances of type I error and so are excluded from the analysis.
Most research involves both results expressed statistically (which requires choice of significance threshold and balancing chances of Type I vs. Type II error) and multiple steps each requiring methodological decisions.
Third, our analyses were more exploratory than confirmatory in nature, with multiple statistical tests performed across the 10 outcomes, thus increasing our chances of Type I error.
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The calculation of intervals accounts for the increased chances of type-1 errors due to multiple comparisons.
As polymorphism detection efforts increase and a higher density of genetic variants across genes become available, the chances of typing causal variants directly, or markers strongly correlated with such variants, is increasing (see Figure 1 for historical overview).
The addition of observational studies can increase greatly the sample size, thereby reducing the chance of type II errors.
To reduce the chance of Type II error, we had to limit the number of covariates (potential confounders) in our models.
Given the high chance of type 2 errors (false negative results) being incurred if p values were adjusted to correct for the number of comparisons made, the p values shown are raw rather than adjusted values.
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CEO of Professional Science Editing for Scientists @ prosciediting.com